Wednesday, August 19, 2020

short notes on Bioreactors

Bioreactor :
A bioreactor refers to any manufactured device or system that supports a biologically active environment.

On the basis of mode of operation, a bioreactor may be classified as batch.

Immobilization is useful for continuously operated processes.


Why are bioreactors used?


The process can be aerobic or anaerobic. Bioreactors are used for making pharmaceutical products such as antibiotics and insulin.

Bioreactors are used for making pharmaceutical products such as antibiotics and insulin. 


What is the difference between bioreactor and fermentor?

           Bioreactors & Fermenters

Fermentation involves the breakdown of certain substances by bacteria or yeast or other microorganisms in the production of beer, wine, or liquor through the action of enzymes. Energy is extracted from carbohydrates in the absence of oxygen.
And At the end of the process, the desired products can be extracted or separated easily. Hence, these bioreactors utilize routinely in industries to produce secondary metabolites such as pharmaceuticals, vitamins and proteins.


What is a bioreactor and how does it work?

Through this mechanism, called the denitrification pathway, nitrate is removed from the tile water before it can enter surface waters.
These microorganisms "eat" the carbon from the woodchips and "breathe" the nitrate from the water. Just as humans breathe in oxygen and breathe out carbon dioxide, these microorganisms breathe in nitrate and breathe out nitrogen gas, 


Bioreactor applications?

They are used in various applications, including basic research and development, and the manufacturing of biopharmaceuticals, food and food additives.


Types :

Photoreactor :- photobioreactor (PBR) is a bioreactor which incorporates some type of light source (that may be natural sunlight or artificial illumination).
                      Photobioreactors are used to grow small phototrophic organisms such as cyanobacteria, algae, or moss plants.
                       Bioreactors are generally used in those industries which are concerned with food, beverages and pharmaceuticals.

Bioreactors for specialized tissues :-
Many cells and tissues, especially mammalian ones, must have a surface or other structural support in order to grow, and agitated environments are often destructive to these cell types and tissues.
Currently, scaling production of these specialized bioreactors for industrial use remains challenging and is an active area of research.

 Sewage treatment :-
Conventional sewage treatment utilises bioreactors to undertake the main purification processes. In some of these systems, a chemically inert medium with very high surface area is provided as a substrate for the growth of biological film. 
                     An extremely simple version of a sewage bioreactor is a septic tank whereby the sewage is left in situ, with or without additional media to house bacteria. 

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